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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cda41f232e0cc22f356e4ca7c749e4b2cc74b8ff807cd22c53f06a0d210b2a5' 
  AND token = 'cRC2yyg/itgMvNpp2xpchy4ON1Itxf19fQk1uzf456I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}