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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1820e58b499ff4c847cf9dbb5884678f1365c6cf54fcfb1f4a3a23c3b41cfc' 
  AND token = 'nMxUB2NI2QCvUjs1fGEmNY2kQrHeu/v4RZUH5UFaWOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}