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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc05c518ce26f3a03bcc1ee726082c7ba6b339f4ff92b1716107983debc0e4d' 
  AND token = '0a3tdufuF4Sv0HWaTIX07yIvE9NK7nizjamgtJ8p0t8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}