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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e3f52e8031e4f8a85984201ab282a0ce3ab4253cd12a21546036e48423b480f' 
  AND token = '/fSDfSEuIppaV+WRHdVBjqxSu1HxOsambJwplCv13wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}