SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73cb1a1ee8077c96dc5f012e45ac8cd62856a6c86926acede52a539ec73807a7' 
  AND token = 'xGc6ABP7cOVjX6muif/VEF16fE88EZmbUP4SFwEuHsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}