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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfd45889782bc64d288589f9af8c4580ef5c5d80d69fc8f337a594b87d7ee1bc' 
  AND token = 'fVQOOPFsQfvSzFnGt3q9+HYqRfSd0HeuYJcBnYYFP50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}