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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187eee9ef1c91bbf111b0060ba31f637045c6a5632583fd2308380f62ce0b053' 
  AND token = '4JF/TXUOY+h3CNC1ibI7eT2WJKa+6g2XmqqS4TFVSog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}