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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eca51eebcf1c6ae567e0f94fe3aadb5822446f7f146ae9ff252287dd864404a9' 
  AND token = 'igVOTX8w2rONQB3Dwf3KsMTE29ULhWVVQ7oKoW3HDfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}