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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49dfcf8c4e5b82fb1665197a12325d83a5b5948dae28e0695d4486b43f55b39d' 
  AND token = 'r+/98Ha6vYRDGDrESw7As9z5GnA00ZGdpBuIUPDaQNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}