SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e61928633a6f69e054c3d472b4b7359c6319b2aa2e1a2acb4d330a9d0244091' 
  AND token = 'bHps0dYvvM99gTrb57MyNG7ZnzALepgbZuE4eZrFHcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}