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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61e6673382b060a74916d9b5cfe7d808ea1c85bef3a3e2bbd04f6a4cd952f8cd' 
  AND token = 'wvcQ2XeUamQjwdgdEQE8orNiPxwp1XWAZN1P1Twa3EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}