SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d5343c12f2ad4e955347016833e6af5abd531be3ca833de53b20261c63c2d4' 
  AND token = '29rGD4c/s4pmk7qiYgOFrF4n1XkOumiQMeT1elkGzDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}