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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df2d0b79a84317a0f1c68680c3bc033b959e65d0f9531f60130ca71a17c94da' 
  AND token = 'OMTJu0KobHuZnzuu+eFwB4FimI96C1HH+mofeuRGae8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}