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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8ad133f8d26370697e6afbc175b8a50fe286de9244d1dc59fda1a18cfd4c615' 
  AND token = 'uZCthA/T3/Bm8uNdQpEeVex56Dp38hYIoCgQlqcrpQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}