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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5bec21b074cd0ffc6a3ce60656ea00fbce0c720e1f94cf7990b5de1f467f80' 
  AND token = 'KJcaOTRkp5Cejak6oAeAD89qS4OTFbyHKhGfSOU6AoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}