SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5458e0f9f0571a63ac1e75bb7c006be698f152ee9a3fcbf4591119b6913c1384' 
  AND token = 'tXZtd0Oxuh0s78Gvs0qudeI3hdKxvORhIw76Ewr/3Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}