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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4151494f46792e46ab38ee39becf6b067f048a78b4d6522e1368880dba92e3' 
  AND token = 'QVGU9XHcDJakZ4lXRXdVYJe2JqeQPtnb1oVmNQFc86Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}