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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e1a1e6afb86f4fd95f0e89fd6ead750925e45af718f60ac98cb85c430a0544' 
  AND token = 'CQ+gzXWgxeP1IleY2P9Ht8JgJ6C61+AWoU8Kj3HFHGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}