SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0d9ed878e9aa4798d1f22cd46c10374011a1c8f825f0574d6b1122e8eddf05' 
  AND token = '51XdjrdnW/xFOsOh2DSsEQXFkgUXdshhSMxa2dSWSOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}