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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64ed3d3954acf902cca81cc45e9b92ab8f4229382efb2d4514a6e3f3e3a99e2' 
  AND token = 'hdrmQWHogIAIYFpwbUx/RBD8gLvqNwO2v0kwnIHz3U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}