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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cf1c53e7cc3fa6401f16947be3bc934d6a6f56917e4a0dd8f0d67f7cdbb9e56' 
  AND token = '549VrOJscG19mBemxYz/nX7T5YQGKGk0TMcRJe2fRWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}