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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a595c6953993f1b851f90c5e481e8434c1c8849d78a7771eb3ed3ed7cb0c5181' 
  AND token = 'I7f43ci+kNnMQWxMk1FJV7BACZI3NS+FDwL3C38lXMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}