SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad66ed3ac956a5a2c88b4d67aedfacf3a823ab86d97b55e8abc3f786270ee88' 
  AND token = 'Zj37N1pO2O4Vn2aUfPyAfVlInGYftwNoYvb+b0jS680=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}