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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9533c9139fd1580b46e6394321c43815b879eec5416a2e2d221599ded4ef1c1e' 
  AND token = 'OFPEDKfTMh5+/7joDzq5WLiyjfTeXTfyLy8pOCZ3FlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}