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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7a3a53b52db3bcb640ad0ec632e2988baabc191e7bc1be63019a99557021643' 
  AND token = 'ZVUjVv0XRGypiemn+r3T3HJOMJoPaJp5hjjVku2P5Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}