SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '788751ab3a67664ffbd2ab79176a6cc9c299b003aecb4f1ed16ed27be6e1c183' 
  AND token = 'vPkV4HdIADXFKxnVnrUxZqv8MMqt/XRDfDnrop/tPms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}