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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fad60fea259391d05bd917aecad7def98968a8774f2ba8f8db294b7c26d0244' 
  AND token = 'WTlZlzSM5syEPdWDhCP1s4SsxwHyLEBWDOy3nfOiC94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}