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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6388f81bf80fa63c098ce945239cf4ddce957cfd1c91183803dbabd40008cc' 
  AND token = 'KmE9LB4YoyTGHKpnj9ope3gbv4uJ4Jspfa2FGXJXDG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}