SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a14778851a32491b51ea2c275e787b05f369ccd508b69183d2e48bab7b6de230' 
  AND token = 'qup7Y+k6W9k0dFA8Oj5RMWk6uDYW7cs4PISqLEAvC64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}