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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50569219d2ab8ee7bc116053721a15f011c6d6c84bec4223f75db16858bef2a' 
  AND token = 'ZR63p1eXRJy9rUXHYH0bUcB3yzpW/A5+avmvR+Uf4pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}