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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed4abeddf3fc6e002937c3d2b24a54a84631fc369feca60f7a1f8bab192ed1d' 
  AND token = 'Hdd1fYuw5qNBoLgNw44rGDlzEBkgchjQ9GRNqtzihW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}