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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6269d07c8b7236a17c4f67e1569fbdd7ae4630a50a44281265e1ea99d6de4733' 
  AND token = 'VxCT6jW/V4r+DUephI15tZBugEfoDxJWCOuQ9r6raWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}