SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d381555ccfb2be6e93ba5dcd2973ceb4d9b6a953c4833980198538e0c8384fd' 
  AND token = 'Ve84e+adrGnM6X990/rlEn1JfCClddeWogd0SamHEsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}