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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dbf85c9d11a48610e833fdeaef2eb9accade4a2fd2178db92e04f5061eac789' 
  AND token = 'GzcOTV7asen3kS5qwsrr7MHkSFBOjY+4E7O4ZZ1sxqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}