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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '351d7a9b6e1a6fdd612a5a61433082552015bc957a34c22a3811f3cfef69e536' 
  AND token = 'GeP/Qu+ro/3UeWXjeiXssUqUvSllQ8Q6ajXOi6nIGPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}