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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4389d6b03406fe67fb8b0c287e2dbf8f659766ec6f62fe0009d7509f48cc323d' 
  AND token = 'xP6KkzllM2vpSDAb6FOWOCQur+EYzLuNXWlBin5m/aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}