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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b8499d821952c0a0321fd92cb062ac0069014e2150dedee1c7c181585c43d5' 
  AND token = 'P3BZIXMGM/TZsHCMT1+ap8yvIuOKB44w6d4ZZZvRHQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}