SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dff629f66f89ce803cdef1bd1db78abccd7216b1170bf1d0cb932a056e5c99f5' 
  AND token = 'Tpi/QwB5nomQTOUixoqHHsrHfQT2WzfSUqic+ucrMxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}