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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d7496b4b181a0484b379b27e75b07b2cc73e8e9a9a5a4eaa6613a37ce8c465' 
  AND token = 'qID/707Nms6M+4ugdB5IU+YxGwvme17NpMUtD6ZaP3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}