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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67c4a821993afeee70d4996e24db7b1a52e44e3024377d3e47a4e9bd8497b4ba' 
  AND token = 'NZqvX0/wT9u3rHwOVyawcz32YLxghKz8LQ60Oilhkfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}