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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc1aefd1d1208008d7cad5c0627c058f525051505cc65d224739b951c015d19f' 
  AND token = 'khHL/CvXlvDrKPPSi/1LA9ytlyHWN3jVMFFVTAmU9VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}