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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a749469eac81857220be6a9ac7a99c9b03d819162aeec1fc77aabc7cd04c5e62' 
  AND token = 'sMVWtmvH0Zdgxy4t8jGMAyqhm5uKzqb5T5u7/GPdguM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}