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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d90fa58287518765183685556561d747cec8b0a711055b82d2616f68bf72b55' 
  AND token = '2UgeAR5fDy8BK1fm+ynLsa3kn4wIuguTHpjp1Ycf6SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}