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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0443bd5624eb5fe241d2d05976ff4962daf06c2c34f7c9fe3b2c5c497eb3bf16' 
  AND token = 'DZ0wXRG5ka9cm47fxLAv5UmgDCC53jGxLHPFMLJo9UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}