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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79787033aae5d050892d5992552362faef16e860fae428c37f3ea57cc9a12ab6' 
  AND token = 'KiXZJ2G052I+yfPiQz1skuIHwXfKj54ecFPKFLnArOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}