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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5333b8cafab4d41137491647ad4527f7aa70b30b2114f25c805c0ed9f6a6ad5e' 
  AND token = 'fZYkZBvmo6j6Vit10AGMpPqfwC0iSX7+Fno47e2ILpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}