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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2308667d55577d9f9a576c8dba8c364422b646e66bf52368caa7006d5e07ea7c' 
  AND token = 'Sh6DjcBcwM+oKP/0XVE8C3z/nqbXzZ7VhdA5sIOhg0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}