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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22ff5b02df854ab880d71ac1bb248d580b3c3023966e5fb6c5cf9e569bc436c' 
  AND token = 'NgqXRwW23ExXAY5L3MToadOdhxio9gPrF8owpHPlLMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}