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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d421b98c79ccd6be1f71f2b94af8f14e6440bd0fac0f4ac73f2fa8797aa8e93' 
  AND token = 'ZJTLirgZ9cmk8TYU+er+k2Voc1JBMCtUqK7hu1S6e+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}