SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b43ba866e020ed0a0af4458890dd0ca24c09bb6ae6ee6b7d442d995bd20117c' 
  AND token = 'bo2tZnEVDxwKBRcbcQBOZW3sovFLiCd7iZ66TVzI1Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}